Virginia L. Rath was born in Montreal, Canada, and emigrated to the United States at the age of six. She received B.S. and M.S. degrees from Stanford University, her Ph.D. in Biophysics and Biochemistry from the University of California at San Francisco and her MBAs from the Haas School of Business at UC Berkeley and the Columbia Business School in New York City. She has over a decade of experience in the discovery and support of drug development in the pre-clinical stage. While at Pfizer, she identified a novel mechanism of inhibition of a diabetes target which led to a Phase III candidate and numerous patents. As Head of Structural Biology at Thios Pharmaceuticals, she led an effort to develop drugs exploiting novel targets involved in sulfation. In 2004, she launched Reciprocal Space Consulting, which provides experimental support for structure based drug design programs in Biotech and Fortune 500 Pharmaceutical companies.
Thiang Yian Wong was born in Kuala Lumpur, Malaysia. She received her Bachelor of Science (Honors) in Biotechnology from the University of Leeds in the U.K. and her Ph.D. in Molecular Biology and Biophysics from the University of Leeds. Working with Michael J. McPherson, her Ph.D. thesis focused on the molecular analysis of an alginate lyase gene and its enzyme product from Klebsiella pneumoniae, a pathogenic microbe isolated from a cystic fibrosis patient. As a Post-Doctoral Research Scientist in the laboratory of Neal L. Schiller at the University of California, Riverside, Dr. Wong studied gene function in the pathogen, Pseudomonas aeruginosa, also isolated from cystic fibrosis patients. Subsequently, she moved to La Jolla to study anthrax toxin proteins in the laboratory of Robert C. Liddington at the Burnham Institute for Medical Research, including studies of small molecule inhibitors of lethal factor. In 2006, Dr. Wong joined Reciprocal Space Consulting in 2006 as a Senior Scientist. She speaks Mandarin, Malay and a little Italian.